Specific genes is expected to play a role in the spread of cancer throughout the body of a woman, according to a new study.Scientists from the U.S. National Cancer Institute (NCI), who operated on the basis of previous research, found in samples of breast tumors in humans and mice that mark specific genes predicts metastasis opportunities, according to the study, published in the journal Cancer Research, published in January.
In the study, one sign of the first gene discovered in mice that increase the risk of breast cancer metastasis by 20-fold. Then, the researchers found signs consistent gene in humans that predict recurrence of disease in four out of five breast cancer patients.
Many experts previously believed metastases is primarily a result of non-inherited mutations in cancer tissue. These findings may help doctors find better treatments in the treatment of breast cancer.
"Our previous studies clearly establish that inherited factors also play an important role in the development of metastasis and may help to distinguish which tumors have a tendency to spread to other body parts," said the studies authors, W. Kent Hunter, leader of Metastasis Susceptibility Section at NCI at the Laboratory of Cancer Biology and Genetics.
"In the future, we hope to ensure women which is more likely to have tumors that will spread, and we can then customize for their specific treatment, and avoid using harsh treatment for those who have a low chance to experience growth," he said.
"Other studies provide additional evidence about the role of inherited genes in breast cancer development in humans," said Hunter.
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